INTRODUCING

MAGELIA

Walk-away automation for library preparation
micro-volume efficiency and improved PCRs
protocol agnostic
Overview
Magelia is an open, benchtop automation platform built for complex molecular biology workflows (NGS library prep and beyond).
It miniaturizes reactions from the µL down to sub-µL volumes using patented confined-reaction and magnetic bead handling technologies — improving consistency, efficiency, and robustness.

Runs are truly walk-away: load samples and reagents, start the protocol, and recover ready-to-use outputs the next morning.
Features
  • High performance on low-input / challenging samples
    Miniaturized, confined reactions improve molecule recovery and reduce failures on scarce material.
    Get actionnable librairies when everything else failed.
  • Compact bench top platform
    Free space on your lab bench. The Magelia sits on a standard lab bench with no external dependencies.
  • Connected, update-ready instrument
    Magelia can be connected to WiFI or Ethernet for automatic updates, notifications, protocols download, and much more.
  • True overnight walk-away automation
    Launch in the evening. Come back to libraries ready for QC / sequencing.
  • Functionalities required to perform complex protocols
    Integrated heating, cooling, thermal cycling, along with many other functionalities make the Magelia a uniquely versatile instrument. See functionalities.
  • Open to commercial kits & chemistries
    Protocol-agnostic platform: adapt workflows without vendor lock-in.
Functionalities
Everything required for full library prep workflows — from bead-based cleanups and size selection to thermal cycling — in a single compact instrument.

Purification

Elution
Heating
Cooling
Mixing
Merging
Capture
Amplification
Labelling
Performances highlights
Magelia consistently outperforms manual processes. In micro-volumes, biology happens faster, and molecules interactions are promoted.

Results obtained from validated workflows:
More from less
✓ PCR-free WGS libraries from 5 ng DNA (50× below typical kit lower limits reported by vendors), with high-quality sequencing metrics.

✓ RNA-seq libraries generated from inputs down to 1 ng total RNA (validated on real workflows).
Operational efficiency
✓ Overnight walk-away runs reduce hands-on time and dependency on scarce expert operators.

✓ Get your workflow working in a few days.

Cleaner data
Improved library cleanliness / reduced background (e.g., fewer adapter dimers) supports higher usable sequencing depth.

rRNA depletion performance can materially impact transcriptome resolution.

Versatility
Built for labs with real-world constraints

  • Core facilities running multiple protocols and unpredictable sample types.
  • Clinical / translational labs needing robustness, traceability, and low-input performance.
  • R&D teams validating new workflows without months of liquid-handler scripting.

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